Jaurnal Stevens Johnson Syindrome

Media Folia Medica Indonesiana
Volume : 43 - No. 2 - 2007-04-01
Author : Bony Pramono
Case Report: Successful Treatment of Stevens Johnson
Syndrome-Toxic Epidermal Necrolysis with Intravenous
Immunoglobulin
Abstrak :
Steven Johnson Syndrome is a serious disease of the skin characterized by triad of erythema exudativum
multiforme lesions affecting skin, orifices and eyes. Immunological basis of this disease is hypersensitivity
type III and IV. The differential diagnosis are Staphylococcal Scalded Skin Syndrome and Toxic Epidermal
Necrolysis. The mainstay of treatment is discontinuation of previously given drugs. Supportive treatment
consisting fluid therapy, skincare, symptomatic and antibiotic for existing skin infection. Intravenous
Immunoglobulins is used in severe skin involvement and severe complications including eyes. The
prognosis is generally good, fatal outcome is usually due to delayed therapy and severe complication.
Keyword :
Steven Johnson Syndrome, Toxic Epidermal Necrolysis, IVIG, prognosis
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